beta-catenin and synaptophysin have a common regulator HMGB1

beta-catenin is regulated by HMGB1
HMGB1 regulates beta-catenin
Regulation(C: HMGB1, T: beta-catenin)
Confidence: Very low
Chromatin protein HMGB2 regulates articular cartilage surface maintenance via beta-catenin pathway. Described in 1 sentence
synaptophysin is regulated by HMGB1
HMGB1 upregulates synaptophysin
Positive_regulation(C: HMGB1, T: synaptophysin)
Confidence: Average
The kinetics of tumour necrosis factor (TNF) production, NO production, activation of p38 mitogen-activated protein kinase (MAPK), p44/42 MAPK- and SAPK/JNK-signalling pathways, nuclear translocation of nuclear factor kappa B (NF-kappaB) and HMGB1-induced upregulation of major histocompatibility complex (MHC) class II and CD86 were analysed. Described in 1 sentence
Downregulation of HMGB1 downregulates synaptophysin
Negative_regulation(C: Negative_regulation(T: HMGB1), T: synaptophysin)
Confidence: Average
Inhibition of the RAGE-amphoterin interaction suppressed activation of p44/p42, p38 and SAP/JNK MAP kinases; molecular effector mechanisms importantly linked to tumour proliferation, invasion and expression of matrix metalloproteinases. Described in 1 sentence
All interactions mentioned for the specific gene symbol in text. The results are not restricted to any specific organism.
All interactions for genes that have these gene symbols as official name or synonym. The results are restricted to specific organisms and synonyms are taken into account.
All interactions for families that contain genes with these gene symbols as official name or synonym. The results group interologs and regulogs together, and synonyms are taken into account for each gene in the gene family.
All interactions mentioned between these specific gene symbols in text. The results are not restricted to any specific organism.
All interactions between genes that have these gene symbols as official name or synonym. The results are restricted to specific organisms and synonyms are taken into account.
All interactions between families that contain genes with these gene symbols as official name or synonym. The results group interologs and regulogs together, and synonyms are taken into account for each gene in the gene family.
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